Volker Spindler Selected Research

Desmosomal Cadherins

1/2018	Mechanisms Causing Loss of Keratinocyte Cohesion in Pemphigus.
1/2018	Atomic Force Microscopy Provides New Mechanistic Insights into the Pathogenesis of Pemphigus.
11/2014	Desmosomes and extradesmosomal adhesive signaling contacts in pemphigus.
2/2014	Desmosomal cadherins and signaling: lessons from autoimmune disease.
2/2013	Peptide-mediated desmoglein 3 crosslinking prevents pemphigus vulgaris autoantibody-induced skin blistering.
10/2011	The extent of desmoglein 3 depletion in pemphigus vulgaris is dependent on Ca(2+)-induced differentiation: a role in suprabasal epidermal skin splitting?
12/2006	Inhibition of Rho A activity causes pemphigus skin blistering.

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Volker Spindler Research Topics

Disease

25	Pemphigus (Pemphigus Vulgaris) 01/2019 - 12/2006
14	Skin Diseases (Skin Disease) 01/2018 - 12/2006
9	Blister (Bulla) 01/2019 - 05/2011
5	Autoimmune Diseases (Autoimmune Disease) 01/2019 - 10/2011
1	Fibrosis (Cirrhosis) 09/2018
1	Macular Degeneration (Age-Related Maculopathy) 09/2018
1	Epiretinal Membrane (Epiretinal Membranes) 09/2018
1	Pancreatic Neoplasms (Pancreatic Cancer) 01/2017
1	Bullous Pemphigoid (Pemphigoid) 01/2017
1	Retinal Perforations 01/2016
1	Carcinoma (Carcinomatosis) 10/2015
1	Neoplasms (Cancer) 10/2015
1	Crohn Disease (Crohn's Disease) 10/2015
1	Sepsis (Septicemia) 07/2015
1	Necrosis 07/2015
1	Septic Shock (Toxic Shock Syndrome) 07/2015
1	Inflammation (Inflammations) 07/2015
1	Cardiomyopathies (Cardiomyopathy) 11/2014
1	Acantholysis 09/2010

Drug/Important Bio-Agent (IBA)

24	AutoantibodiesIBA 01/2019 - 12/2006
14	DesmogleinsIBA 01/2019 - 09/2007
7	Desmosomal CadherinsIBA 01/2018 - 12/2006
7	Immunoglobulin G (IgG)IBA 01/2018 - 12/2006
6	Keratins (Keratin)IBA 01/2018 - 12/2006
4	Cadherins (E-Cadherin)IBA 12/2015 - 12/2010
3	Cell Adhesion MoleculesIBA 12/2015 - 09/2010
3	p38 Mitogen-Activated Protein KinasesIBA 06/2014 - 12/2006
3	Desmoglein 3IBA 02/2013 - 09/2007
3	rho GTP-Binding Proteins (rho GTP-Binding Protein)IBA 05/2011 - 09/2007
2	Desmoglein 2IBA 01/2017 - 10/2015
2	DesmocollinsIBA 01/2017 - 10/2009
2	Peptides (Polypeptides)IBA 11/2014 - 02/2013
2	Proteins (Proteins, Gene)FDA Link 05/2011 - 09/2007
2	Desmoglein 1IBA 09/2007 - 12/2006
1	CortactinIBA 01/2019
1	Dipeptidyl-Peptidase IV InhibitorsIBA 01/2017
1	Dimethyl FumarateIBA 01/2017
1	Chimeric Antigen ReceptorsIBA 01/2017
1	Dapsone FDA Link 01/2017
1	Doxycycline (Periostat)FDA LinkGeneric 01/2017
1	Leukotriene B4IBA 01/2017
1	Type 4 Cyclic Nucleotide PhosphodiesterasesIBA 01/2017
1	brilliant blue (brilliant blue FCF)IBA 01/2016
1	AntigensIBA 10/2015
1	Epithelial Cell Adhesion MoleculeIBA 10/2015
1	LipopolysaccharidesIBA 07/2015
1	3- (formylhydroxyamino)- 2- (3- phenyl- 1- propyl)butanoic acid (2,2- dimethyl- 1- methylcarbamoyl- 1- propyl)amideIBA 07/2015
1	DisintegrinsIBA 07/2015
1	Metalloproteases (Metalloproteinases)IBA 07/2015
1	cadherin 5IBA 07/2015
1	Receptors for Activated C KinaseIBA 09/2014
1	Green Fluorescent ProteinsIBA 09/2014
1	Desmoplakins (Desmoplakin)IBA 09/2014
1	Octoxynol (Triton X 100)IBA 09/2014
1	adducinIBA 05/2014
1	Protein Kinase CIBA 10/2011
1	GTP Phosphohydrolases (GTPases)IBA 05/2011
1	Adenosine (Adenocard)FDA LinkGeneric 12/2010
1	jasplakinolideIBA 09/2010
1	Cytochalasin DIBA 09/2010
1	AntibodiesIBA 09/2007

Therapy/Procedure

2	Traction 09/2018 - 01/2016
2	Vitrectomy 09/2018 - 01/2016
2	Lasers (Laser) 10/2009 - 12/2006